Familial Aggregation Pattern of Non-Syndromic Combined Aplasia of Maxillary Lateral Incisors and Third Molars

Congenitally missing teeth, the most common dental anomaly, refers to teeth whose germ did not develop sufficiently allow differentiation of tissues.
 This study aimed determine importance genetic investigations on oral health-related quality life in children with congenitally lateral incisors.
 We are presenting a performed by A.S. Division Medical Genetics, Bucharest, Romania, case patient (16-year-old boy) bilateral maxillary incisor agenesis permanent dentition, hereditary, non-syndromic familial hypodontia three successive generations, which suggest an autosomal dominant inheritance, combined aplasia third molars.
 The visual examination and radiological exam were completed photographic examination, family historyinvestigation, pedigree, analysis studied family’s genealogical tree, after acquiring signed informed consent patient.
 incisors, calculation anomaly recurrence risk amongst offspring, direct specialized monitoring affected families, order limit potential complications.